Scientists Cure Bald Mice

A new discovery offers hope for finding a treatment for hair loss from male-pattern baldness, scarring alopecia, and scalp injury. Studies done on adult mice at the University of Pennsylvania School of Medicine have shown that hair follicles can be regenerated in adult mammals, something that was once thought to be impossible.

The research focused on the healing process of deep skin wounds on the backs of adult mice. It is known that mammals are able to heal from injuries, but it was accepted that they could not replace lost body parts, such as limbs or hair follicles. In this study, the researchers found a way to amplify the natural healing process and reactivate dormant embryonic molecular pathways. Stem cells, which are master cells capable of transforming into other cell types, were sent to the damaged skin. The stem cells reprogrammed epidermal cells, which are cells that don't normally make hair follicles, and instructed them to make a follicle. The new follicle functioned normally, cycling thru the hair growth cycle and producing hair.

The findings of the research will be used to develop treatments not only for male-pattern baldness, but also for hair loss due to diseases and injuries that destroy hair follicles. It is also thought that the information will lead to scar free surgery. While products available for actual use in humans will take years to develop, at least there is hope on the horizon for an effective baldness remedy.